CPA1 antibody (CF®647)

Catalog No. ABIN7650514

This Mouse Monoclonal antibody specifically detects CPA1 in WB, IHC and IHC (fp). It exhibits reactivity toward Human.

Quick Overview for CPA1 antibody (CF®647) (ABIN7650514)

Target: CPA1 (Carboxypeptidase A1 (Pancreatic) (CPA1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CPA1 antibody is conjugated to CF®647

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: CPA1-2713

Product Details anti-CPA1 Antibody (CF®647)

Purpose: Carboxypeptidase A1 / CPA1 (Pancreatic Cancer Marker)(CPA1/2713), CF647 conjugate

Characteristics: Carboxypeptidase A1 (CPA1) is a secreted zinc metalloprotease that is highly expressed in pancreatic tissue. It catalyzes the release of C-terminal amino acids from a variety of proteins, thereby playing a key role in protein digestion and degradation. Human pancreatic procarboxypeptidase A exists as three different active forms, two of which are carboxypeptidase A1 (CPA1) and carboxypeptidase A2 (CPA2). Abnormal levels of CPA1 are associated with pancreatic cancer, suggesting a possible role in either tumor progression or tumor suppression events. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant full-length human CPA1 protein

Isotype: IgG, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Positive Control: Pancreas

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from light

Storage: 4 °C

Storage Comment:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Expiry Date: 24 months

Target Details for CPA1

Target: CPA1 (Carboxypeptidase A1 (Pancreatic) (CPA1))

Alternative Name: Carboxypeptidase A1

Background:

Synonyms: Carboxypeptidase A1, CPA1

Gene Symbol: CPA1

Tissue Expression: Pancreas

Molecular Weight: 47 kDa

Gene ID: 1357

UniProt: P15085