CTNND1 antibody (CF®740)

Catalog No. ABIN7650595

This Mouse Monoclonal antibody specifically detects CTNND1 in . It exhibits reactivity toward Human and Rat.

Quick Overview for CTNND1 antibody (CF®740) (ABIN7650595)

Target: CTNND1 (Catenin (Cadherin-Associated Protein), delta 1 (CTNND1))

Reactivity: Human, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This CTNND1 antibody is conjugated to CF®740

Application: Please inquire

Clone: 25a

Product Details anti-CTNND1 Antibody (CF®740)

Purpose: Catenin, delta-1 (CTNND1) (pTyr96) (25a), CF740 conjugate

Characteristics: Delta 1 catenin, also known as p120 catenin, is a tyrosine kinase substrate that is phosphorylated in Src transformed cells or in response to growth factor stimulation. Like beta- and gamma-catenin, p120 Catenin directly associates with the cytoplasmic C-terminus of E-Cadherin via its Arm domain and may similarly interact with other cadherins. The catenin/cadherin complexes play an important role mediating cellular adhesion, including adherens junctions.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Mouse p120 Catenin (pY96)

Isotype: IgG1, kappa

Application Details

Application Notes: For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry

Comment:

Positive Control: Carcinoma

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % rBSA, 0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from light

Storage: 4 °C

Storage Comment:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Expiry Date: 24 months

Target Details for CTNND1

Target: CTNND1 (Catenin (Cadherin-Associated Protein), delta 1 (CTNND1))

Alternative Name: Catenin, Delta-1

Background:

Synonyms: Delta 1 cadherin, Catenin delta-1, Cadherin-associated Src substrate (CAS), Catenin (cadherin associated protein) delta 1, CTNND1, p120 catenin

Gene Symbol: CTNND1

Tissue Expression: Epithelial cells

Molecular Weight: 120 kDa

Gene ID: 1500

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling