CD38 antibody (CF®568)
Quick Overview for CD38 antibody (CF®568) (ABIN7651327)
Target
See all CD38 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- CD38 (ADP Ribosyl Cyclase 1)(FS02), CF568 conjugate
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Characteristics
- This antibody reacts with a type II membrane glycopeptide with a transmembrane sequence near the NH2-terminus. CD38 is a type II transmembrane glycoprotein that is present on early B- and T-cell lineages and activated B- and T-cells but is absent from most mature resting peripheral lymphocytes. CD38 is also found on thymocytes, pre-B cells, germinal center B-cells, mitogen-activated T-cells, monocytes and Ig-secreting plasma cells. CD38 is expressed on CD34 cells. The CD34 CD38- population of hematopoietic stems cells defines the most pluripotent cells (e.g. blast colony forming cells).
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Immunogen
- Human CD38
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Isotype
- IgG1, kappa
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Application Notes
- For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry
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Comment
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Positive Control: CCRF-CEM cells, Tonsil, Spleen or Skin
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.1 mg/mL
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Buffer
- PBS, 0.1 % BSA, 0.05 % azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Protect from light
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Storage
- 4 °C
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Storage Comment
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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Expiry Date
- 24 months
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- CD38
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Background
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Synonyms: Acute Lymphoblastic Leukemia Cells Antigen, ADP Ribosyl Cyclase 1, cADP-ribose Hydrolase 1, CD38H, NAD( ) Nucleosidase, NIM-R5 Antigen, p45, T10
Gene Symbol: CD38
Tissue Expression: B-cells|T-cells
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Molecular Weight
- ~45 kDa (Glycoprotein), 35 kDa (protein core)
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Gene ID
- 952
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UniProt
- P28907
Target
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