CD38 antibody (CF®740)

Catalog No. ABIN7651330

This Mouse Monoclonal antibody specifically detects CD38 in . It exhibits reactivity toward Human.

Quick Overview for CD38 antibody (CF®740) (ABIN7651330)

Target: CD38

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD38 antibody is conjugated to CF®740

Application: Please inquire

Clone: AT2

Product Details anti-CD38 Antibody (CF®740)

Purpose: CD38(AT2), CF740 conjugate

Characteristics: This MAb reacts with a 45 kDa glycopeptide, which is a type II membrane glycoprotein with a transmembrane sequence near the NH2 terminus. CD38 is a type II transmembrane glycoprotein that is present on early B- and T-cell lineages and activated B- and T-cells but is absent from most mature resting peripheral lymphocytes. CD38 is also found on thymocytes, pre-B cells, germinal center B-cells, mitogen-activated T-cells, monocytes and Ig-secreting plasma cells. CD38 is expressed on CD34 cells. The CD34 CD38- population of hematopoietic stems cells defines the most pluripotent cells (e.g. blast colony forming cells). Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: human T cell line CCRF-CEM

Isotype: IgG3, kappa

Application Details

Application Notes: For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry

Comment:

Positive Control: CCRF-CEM cells, Tonsil, Spleen or Skin

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % rBSA, 0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from light

Storage: 4 °C

Storage Comment:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Expiry Date: 24 months

Target Details for CD38

Target: CD38

Background:

Synonyms: Acute Lymphoblastic Leukemia Cells Antigen, ADP Ribosyl Cyclase 1, cADP-ribose Hydrolase 1, CD38H, NAD( ) Nucleosidase, NIM-R5 Antigen, p45, T10

Gene Symbol: CD38

Tissue Expression: B-cells|T-cells

Molecular Weight: ~45 kDa (Glycoprotein), 35 kDa (protein core)

Gene ID: 952

UniProt: P28907