Recombinant F13A1 antibody (AA 46-181) (CF®640R)

Catalog No. ABIN7652466

This anti-F13A1 antibody is a Rabbit Monoclonal antibody detecting F13A1 in IHC and IHC (fp). Suitable for Human.

Quick Overview for Recombinant F13A1 antibody (AA 46-181) (CF®640R) (ABIN7652466)

Target: F13A1 (Coagulation Factor XIII, A1 Polypeptide (F13A1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This F13A1 antibody is conjugated to CF®640R

Application: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: F13A1-3772R

Product Details anti-F13A1 Antibody (CF®640R)

Binding Specificity: AA 46-181

Purpose: Factor XIIIa (Coagulation Factor XIIIA Chain)(F13A1/3772R), CF640R conjugate

Characteristics: Recognizes a protein of 83 kDa, which is identified as Factor XIIIa. It has been identified in platelets, megakaryocytes, and fibroblast-like mesenchymal or histiocytic cells in the placenta, uterus, and prostate, monocytes and macrophages and dermal dendritic cells. Anti-factor XIIIa has been found to be useful in differentiating between dermatofibroma (almost all cases are positive), dermatofibrosarcoma protuberans (-/ ) and desmoplastic malignant melanoma (-). Anti-factor XIIIa positivity is also seen in capillary hemagioblastoma, hemangioendothelioma, hemangiopericytoma, xanthogranuloma, xanthoma, hepatocellular carcinoma, glomus tumor, and meningioma. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant fragment of human Factor XIIIa protein (aa46-181)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Positive Control: Human placenta tissue (IHC).

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from light

Storage: 4 °C

Storage Comment:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Expiry Date: 24 months

Target Details for F13A1

Target: F13A1 (Coagulation Factor XIII, A1 Polypeptide (F13A1))

Alternative Name: Factor-XIIIa

Background:

Synonyms: Coagulation factor XIII A chain, Coagulation factor XIII A1 polypeptide, F13A, F13a1, Fibrin stabilizing factor, A subunit, Fibrinoligase, FSF, A subunit, Protein-glutamine gamma-glutamyltransferase A chain, TGase, Transglutaminase. plasma

Gene Symbol: F13A1

Tissue Expression: Platelets|Uterus|Megakaryocytes|Monocytes/macrophages|Placenta|Prostate

Molecular Weight: 83 kDa

Gene ID: 2162

UniProt: P00488