ABCB5 antibody (AA 841-883)

Catalog No. ABIN731933

The Rabbit Polyclonal anti-ABCB5 antibody has been validated for ELISA, IHC (p), IF (cc), IF (p) and IHC (fro). It is suitable to detect ABCB5 in samples from Mouse. There is 1 publication available.

Quick Overview for ABCB5 antibody (AA 841-883) (ABIN731933)

Target: ABCB5 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 5 (ABCB5))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABCB5 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-ABCB5 Antibody

Binding Specificity: AA 841-883

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ABCB5

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-ABCB5 antibody (ABIN731933)

Kaushik, Venugopal, Ramamoorthy, Standing, Subramaniam, Umar, Jensen, Anant, Mammen: "Honokiol inhibits melanoma stem cells by targeting notch signaling." in: Molecular carcinogenesis, (2014) (PubMed).

Target Details for ABCB5

Target: ABCB5 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 5 (ABCB5))

Alternative Name: ABCB5

Background:

Synonyms: ABCB5beta, EST422562, ABCB5alpha, ATP-binding cassette sub-family B member 5, ABCB5 P-gp, P-glycoprotein ABCB5, ABCB5

Background: Drug efflux transporter present in a number of stem cells that acts as a regulator of cellular differentiation. Able to mediate efflux from cells of the rhodamine dye and of the therapeutic drug doxorubicin. Specifically present in limbal stem cells, where it plays a key role in corneal development and repair.

Gene ID: 340273

UniProt: Q2M3G0