EBV EA p55,p50 antibody (CF®740)

Catalog No. ABIN7653709

This Mouse Monoclonal antibody specifically detects EBV EA p55,p50 in IF, IP and WB. It exhibits reactivity toward Epstein-Barr Virus (EBV).

Quick Overview for EBV EA p55,p50 antibody (CF®740) (ABIN7653709)

Target: EBV EA p55,p50 (Epstein-Barr Virus Early Antigen p55,p50 (EBV EA p55,p50))

Reactivity: Epstein-Barr Virus (EBV)

Host: Mouse

Clonality: Monoclonal

Conjugate: This EBV EA p55,p50 antibody is conjugated to CF®740

Application: Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)

Clone: 1108-1

Product Details anti-EBV EA p55,p50 Antibody (CF®740)

Purpose: p55,50 EBV-Early Antigen(1108-1), CF740 conjugate

Characteristics: Epstein-Barr virus (EBV), also designated human herpesvirus 4 (HHV-4), is a member of the herpesvirus family and is one of the most common human viruses. EBV infects B cells and, though often asymptomatic, it can cause infectious mononucleosis, a disease characterized by fatigue, fever, sore throat and muscle soreness. The EBV-induced early antigens (Ea) are among several antigen complexes that have been identified in EBV-infected cells. The Ea complex is composed of diffuse (Ea-D) and restricted (Ea-R) components. The activity of Ea-D is suppressed during latent infection. BMRF1, the gene that encodes for Ea-D, is closely associated with the gene encoding for EBV DNA polymerase, and Ea-D is essential for the activity of this polymerase. Ea-D forms a complex with EBV DNase and, together, they may play a role in viral replication. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Isotype: IgG1, kappa

Application Details

Application Notes: Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunofluorescence: 0.5-1 μg/mL. Optimal dilution for a specific application should be determined by user

Comment:

Positive Control: EBV-infected cells or tissues

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % rBSA, 0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from light

Storage: 4 °C

Storage Comment:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Expiry Date: 24 months

Target Details for EBV EA p55,p50

Target: EBV EA p55,p50 (Epstein-Barr Virus Early Antigen p55,p50 (EBV EA p55,p50))

Alternative Name: p55,50 EBV Early Antigen

Target Type: Viral Protein

Background: EBNA1, EBV nuclear antigen 1, Epstein Barr nuclear antigen 1, Human Herpesvirus 4 (HHV4)

Molecular Weight: 50/55 kDa doublet