Progesterone antibody (CF®740)

Catalog No. ABIN7658932

This Mouse Monoclonal antibody specifically detects Progesterone in . It exhibits reactivity toward Various Species.

Quick Overview for Progesterone antibody (CF®740) (ABIN7658932)

Target: Progesterone

Reactivity: Various Species

Host: Mouse

Clonality: Monoclonal

Conjugate: This Progesterone antibody is conjugated to CF®740

Application: Please inquire

Clone: 6-5E-10B

Product Details anti-Progesterone Antibody (CF®740)

Purpose: Progesterone(6-5E-10B), CF740 conjugate

Characteristics: This MAb is specific for progesterone. It exhibits minimal cross reactivity with related compounds in ELISA. It reacts with Progesterone-11a-HMS-BSA: 100 % , 5-beta-Pregnane-3,20-dione: 48 %, 5-alpha-Pregnane-3,20-dione: 26.4 %, 17-alpha-Hydroxyprogesterone: 2.5 % and 20-alpha-Hydroxyprogesterone: 0.04 %. Progesterone is a steroid hormone synthesized from the cholesterol derivative, pregnenolone, in the cortex of the adrenal gland. Progesterone is secreted by the corpus luteum and acts to prepare the endometrium for the implantation of a fertilized egg. During pregnancy, it is secreted by the placenta to prevent spontaneous abortion and to stimulate the development of mammary tissue to produce milk. Thus, progesterone plays a central role in the reproductive events associated with the establishment and maintenance of pregnancy. Luteinized theca cells of normal ovary secrete progesterone. The determination of progesterone concentrations in the body fluids is of great value for endocrinological investigations in women. This MAb may prove useful in identification of ovarian tumors.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Progesterone- 11a-hemisuccinate conjugated to bovine serum albumin (Pr11a-HMS-BSA)

Isotype: IgG1, kappa

Application Details

Application Notes: For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry

Comment:

Positive Control: Ovary or Placenta

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % rBSA, 0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from light

Storage: 4 °C

Storage Comment:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Expiry Date: 24 months

Target Details for Progesterone

Target: Progesterone

Target Type: Hormone

Background: Pregn 4 ene 3 20 dione, Pregn 4 ene 3 20 dione

Molecular Weight: 314.46Da