PSAP antibody (CF®647)

Catalog No. ABIN7659218

The Mouse Monoclonal anti-PSAP antibody has been validated for IHC and IHC (fp). It is suitable to detect PSAP in samples from Human.

Quick Overview for PSAP antibody (CF®647) (ABIN7659218)

Target: PSAP (Prostate Specific Acid Phosphatase (PSAP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PSAP antibody is conjugated to CF®647

Application: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: PASE-4LJ

Product Details anti-PSAP Antibody (CF®647)

Purpose: Prostate Specific Acid Phosphatase (PSAP)(PASE/4LJ), CF647 conjugate

Characteristics: Recognizes a protein of 52 kDa, identified as prostate specific acid phosphatase (PSAP). This enzyme catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland. PSAP is found in non-neoplastic adult and fetal prostatic glands, primary and metastatic prostatic carcinomas. It shows no staining in granulocytes, osteoclasts, parietal cells of the stomach, liver cells, renal cell or breast carcinomas. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Prostatic acid phosphatase Purified from human seminal plasma

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Positive Control: PC12 cells. Normal prostate or prostate carcinoma.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from light

Storage: 4 °C

Storage Comment:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Expiry Date: 24 months

Target Details for PSAP

Target: PSAP (Prostate Specific Acid Phosphatase (PSAP))

Alternative Name: Prostate-Specific Acid Phosphatase

Background:

Synonyms: 5'-nucleotidase (5'-NT), Acid phosphatase prostate, ACP3, Ecto-5'-nucleotidase, Prostatic acid phosphatase (PAP), Prostatic acid phosphatase, Thiamine monophosphatase (TMPase)

Gene Symbol: PAX2

Tissue Expression: Prostate

Molecular Weight: 52 kDa

Gene ID: 5076

UniProt: P15309