CD1d antibody

Catalog No. ABIN7669993

The Rat Monoclonal anti-CD1d antibody has been validated for FACS. It is suitable to detect CD1d in samples from Mouse.

Quick Overview for CD1d antibody (ABIN7669993)

Target: CD1d (CD1D) (CD1d Molecule (CD1D))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD1d antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: 1B1

Product Details anti-CD1d Antibody

Purpose: Purified Anti-Mouse CD1d Antibody[1B1]

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: ≥ 1 mg/mL

Buffer: Phosphate buffered solution, pH 7.2, containing 0.05 % proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze / thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for CD1d

Target: CD1d (CD1D) (CD1d Molecule (CD1D))

Alternative Name: CD1d

Background: Antigen-presenting glycoprotein CD1d1,Cd1d1,CD1d.1,Cd1d1,Cd1.1,CD1d, known as CD1.1 and Ly-38, is a 48 kD type I membrane glycoprotein with structural similarities to MHC class I and is non-covalently associated with β2-microglobulin. In humans, CD1 family consists of group I proteins (CD1a, CD1b, and CD1c), group II (CD1d), and group III (CD1e). But CD1d is the only CD1 Molecule has been found in mouse. Mouse CD1d has broad tissue distribution, and is found on leukocytes, dendritic cells, epithelial cells, and thymocytes. CD1d plays a role in non-peptide glycolipid antigen presentation to CD1d-restricted T cells. It has been shown that PKCδ is a critical regulator of CD1d-mediated antigen presentation.

UniProt: P11609

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process