TCR Vbeta1 antibody

Catalog No. ABIN7670130

This Rat Monoclonal antibody specifically detects in FACS. It exhibits reactivity toward Human.

Quick Overview for TCR Vbeta1 antibody (ABIN7670130)

Target: TCR Vbeta1

Reactivity: Human

Host: Rat

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Flow Cytometry (FACS)

Clone: BL37-2

Product Details

Purpose: Purified Anti-Human TCRVβ1 Antibody[BL37.2]

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: ≥ 1 mg/mL

Buffer: Phosphate buffered solution, pH 7.2, containing 0.05 % proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze / thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details

Target: TCR Vbeta1

Alternative Name: TCRVbeta1

Background: TRBV,TRBV9,TCR Vβ1 is a variant of the TCR Vβ chain that is expressed by a subset of αβ+ T cells. Aberrant expression of TCR Vβ chains has been associated with infection and cancer. TCR Vβ1 is reported to be preferably used by autoreactive T cells in a model of autoimmune thyroiditis and diabetes. Skewing of TCR Vβ repertoire to Vβ1 and Vβ9 has also been reported in patients with multiple sclerosis, reactive arthritis, and Kawasaki disease.

UniProt: A0A0B4J1U6