CD1d antibody

Catalog No. ABIN7670151

This Rat Monoclonal antibody specifically detects CD1d in FACS. It exhibits reactivity toward Mouse.

Quick Overview for CD1d antibody (ABIN7670151)

Target: CD1d (CD1D) (CD1d Molecule (CD1D))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD1d antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: 1B1

Product Details anti-CD1d Antibody

Purpose: AF/LE Purified Anti-Mouse CD1d Antibody[1B1]

Endotoxin Level: Low Endotoxin

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: ≥ 1 mg/mL

Buffer: Sterile PBS. < 1.0 EU per mg of the antibody as determined by the LAL method.

Preservative: Azide free

Handling Advice: avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Expiry Date: 12 months

Target Details for CD1d

Target: CD1d (CD1D) (CD1d Molecule (CD1D))

Alternative Name: CD1d

Background: Antigen-presenting glycoprotein CD1d1,Cd1d1,CD1d.1,Cd1d1,Cd1.1,CD1d, known as CD1.1 and Ly-38, is a 48 kD type I membrane glycoprotein with structural similarities to MHC class I and is non-covalently associated with β2-microglobulin. In humans, CD1 family consists of group I proteins (CD1a, CD1b, and CD1c), group II (CD1d), and group III (CD1e). But CD1d is the only CD1 Molecule has been found in mouse. Mouse CD1d has broad tissue distribution, and is found on leukocytes, dendritic cells, epithelial cells, and thymocytes. CD1d plays a role in non-peptide glycolipid antigen presentation to CD1d-restricted T cells. It has been shown that PKCδ is a critical regulator of CD1d-mediated antigen presentation.

UniProt: P11609

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process