IL29 antibody

Catalog No. ABIN7670666

This Mouse Monoclonal antibody specifically detects IL29 in ELISA. It exhibits reactivity toward Human.

Quick Overview for IL29 antibody (ABIN7670666)

Target: IL29 (Interleukin 29 (IL29))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL29 antibody is un-conjugated

Application: ELISA

Clone: 1A6

Product Details anti-IL29 Antibody

Purpose: IL-29/IFN-λ1 Monoclonal Antibody(Capture/Detector)

Purification: Protein A/G Purification

Immunogen: Recombinant Human IL-29/IFN-lambda1 protein expressed by Mammalian

Isotype: IgG1

Application Details

Application Notes: ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Preservative: Without preservative

Handling Advice: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Expiry Date: 12 months

Target Details for IL29

Target: IL29 (Interleukin 29 (IL29))

Alternative Name: IL-29/IFN-lambda1

Background: InterLeukin-29(IL-29),IFNL1,ZCYTO21,Interferon Lambda-1,IFN-Lambda-1,Cytokine Zcyto21,IL29,Cytokine with antiviral,antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense,predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of Il10RB and IFNlR1,and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG),which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNlR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.

UniProt: Q8IU54