Fc gamma RII (CD32) antibody (APC)

Catalog No. ABIN7672707

The Mouse Monoclonal anti- antibody has been validated for FACS. It is suitable to detect in samples from Human.

Quick Overview for Fc gamma RII (CD32) antibody (APC) (ABIN7672707)

Target: Fc gamma RII (CD32)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: APC

Application: Flow Cytometry (FACS)

Clone: IV-3

Product Details

Purpose: APC Anti-Human CD32 Antibody

Purification: 0

Purity: 0

Isotype: IgG2b, kappa

Application Details

Application Notes: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: 4 °C

Storage Comment: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details

Target: Fc gamma RII (CD32)

Alternative Name: CD32

Background:

Synonyms: IGFR2|CD32|CDw32|FCG2|FCGR2B|Fc-gamma RII-b|Fc-gamma-RIIb|FcRII-b|IgG Fc receptor II-b|Low affinity immunoglobulin gamma Fc region receptor II-b

Background: CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcγRII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform).

Molecular Weight: 0

Gene ID: 2212

UniProt: P31994