CD16 antibody (PE-Cy7)

Catalog No. ABIN7674107

This Rat Monoclonal antibody specifically detects CD16 in FACS. It exhibits reactivity toward Mouse.

Quick Overview for CD16 antibody (PE-Cy7) (ABIN7674107)

Target: CD16

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD16 antibody is conjugated to PE-Cy7

Application: Flow Cytometry (FACS)

Clone: 2-4G2

Product Details anti-CD16 Antibody (PE-Cy7)

Purpose: PE-Cy7 Anti-Mouse CD16/32 Antibody

Purification: 0

Purity: 0

Isotype: IgG2b, kappa

Application Details

Application Notes: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: 4 °C

Storage Comment: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for CD16

Target: CD16

Alternative Name: CD16

Background:

Synonyms: CD16a/b|CD32|CD32A/B|FCG2A|FCGR2A/BFCGR3|FCGR3A/B|Fc fragment of IgG low affinity IIIa/b receptor|Fc fragment of IgG low affinity IIIb receptor|Fc fragment of IgG low affinity IIa/b receptor|Fc gamma RIIa/bFc gamma receptor III A/B|FcGR

Background: CD16 is low affinity IgG Fc receptor III (FcR III) and CD32 is FcR II. CD16/CD32 are expressed on B cells, monocytes/macrophages, NK cells, granulocytes, mast cells, and dendritic cells. The Fc receptors bind antibody-antigen immune complexes and mediate adaptive immune responses.

Molecular Weight: 0

Gene ID: 1413014131

UniProt: P08508, P08101

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process