MSH alpha (AA 138-150) antibody

Catalog No. ABIN735323

The Rabbit Polyclonal anti- antibody has been validated for WB, ELISA and IHC (p). It is suitable to detect in samples from Human, Rat and Mouse. There is 1 publication available.

Quick Overview for MSH alpha (AA 138-150) antibody (ABIN735323)

Target: MSH alpha

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details

Binding Specificity: AA 138-150

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide of human Alpha-MSH

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References

Jussila, Huotari-Orava, Ylianttila, Partonen, Snellman: "Narrow-band ultraviolet B radiation induces the expression of β-endorphin in human skin in vivo." in: Journal of photochemistry and photobiology. B, Biology, Vol. 155, pp. 104-8, (2016) (PubMed).

Target Details

Target: MSH alpha

Alternative Name: alpha MSH

Background:

Synonyms: LPH, MSH, NPP, POC, ACTH, CLIP, Pro-opiomelanocortin, POMC, Corticotropin-lipotropin

Background: ACTH stimulates the adrenal glands to release cortisol. MSH (melanocyte-stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes. Beta-endorphin and Met-enkephalin are endogenous opiates.

Gene ID: 5443

UniProt: P01189

Pathways: Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity