The Mouse Monoclonal anti-HSV gD antibody has been validated for ELISA, IF and LF. It is suitable to detect HSV gD in samples from Herpes Simplex Virus (HSV).
Catalog No. ABIN7794804
Quick Overview for HSV gD antibody (ABIN7794804)
Target
HSV gD
(Herpes Simplex Virus, Glycoprotein D (HSV gD))
Reactivity
Herpes Simplex Virus (HSV)
Host
Mouse
Clonality
Monoclonal
Conjugate
This HSV gD antibody is un-conjugated
Application
ELISA, Immunofluorescence (IF), Lateral Flow (LF)
Clone
HSV-7315
Purpose
Anti-Herpes Simplex Virus, gD (HSV-7315)
Specificity
Anti-HSV (Clone HSV-7315) has known reactivity for glycoprotein D (gD) of HSV 1 & 2. Antigen Glycoprotein D, gD Background Herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) are two closely related enveloped DNA viruses that are members of the Herpesviridae family of viruses. HSV is a neurotropic virus that initially infects and replicates in epithelial cells of the mucosal epithelium before it establishes lifelong latent infection within sensory neurons. While both viruses can cause genital infection, HSV-2 is most often the cause of these infections. HSV-1 is typically spread during childhood and has a global prevalence of about 90 % . Both viruses can be spread to other tissues via contact with infected skin or mucous membranes. Glycoprotein D (gD) is the major receptor binding protein of HSV and binds to at least one of the three known entry receptors herpesvirus entry mediator (HVEM), nectin-1, and 3-O sulfated heparan sulfate.
Purification
This monoclonal antibody is purified by protein A chromatography or sequential differential precipitations.
Formulated in 0.01 M phosphate buffered saline, pH 7.2 and contains 0.1 % sodium azide. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
This purified antibody is stable when stored at 2-8°C. Do not freeze.
Target
HSV gD
(Herpes Simplex Virus, Glycoprotein D (HSV gD))