EBOV VP40 antibody

Catalog No. ABIN7794821

This Mouse Monoclonal antibody specifically detects EBOV VP40 in ELISA, WB and BP. It exhibits reactivity toward Ebola Virus.

Quick Overview for EBOV VP40 antibody (ABIN7794821)

Target: EBOV VP40 (Ebola Virus Matrix protein VP40 (EBOV VP40))

Reactivity: Ebola Virus

Host: Mouse

Clonality: Monoclonal

Conjugate: This EBOV VP40 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Blocking Peptide (BP)

Clone: EB-977

Product Details anti-EBOV VP40 Antibody

Purpose: Anti-Ebola Virus, VP40 (EB-977)

Specificity: Anti-Ebola Virus (Clone EB-977) has known reactivity for the viral antigen VP40 of Sudan and Zaire strains (reacts with VLPs). Background Ebola virus is a highly infectious and deadly enveloped RNA virus that belongs to the Filoviridae family. It causes severe and often fatal hemorrhagic fever in humans and non-human primates. Ebola is considered endemic in certain parts of Africa where outbreaks have occurred in various countries such as the Democratic Republic of Congo, Sudan, Guinea, Libera, Sierra Leone, and Uganda. VP40 is a matrix protein of Ebola virus that is the most abundantly expressed viral protein during infection. The protein plays an important role in viral assembly and budding with exogenous expression of VP40 being sufficient to induce the formation of viral-like particles. VP40 can oligomerize and the different oligomeric states have distinct functions during infection the octameric confirmation plays a critical role in regulating viral transcription while hexamers localize to the plasma membrane. Because of its critical role in the viral life cycle and abundance, VP40 has been used in diagnostic testing as well as potential therapeutics.

Purification: This monoclonal antibody is purified by protein A chromatography or sequential differential precipitations.

Purity: ≥90 %

Isotype: IgG2b

Application Details

Application Notes: ELISA: 1:20 - 1:200,WB

Restrictions: For Research Use only

Handling

Concentration: 1 μg/mL

Buffer: Formulated in 0.01 M phosphate buffered saline, pH 7.2 and contains 0.1 % sodium azide. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: This purified antibody is stable when stored at 2-8°C. Do not freeze.

Target Details for EBOV VP40

Target: EBOV VP40 (Ebola Virus Matrix protein VP40 (EBOV VP40))

Alternative Name: Ebola Virus, VP40

Target Type: Viral Protein

Background: EB,