Influenza A NS1 antibody

Catalog No. ABIN7794992

This Rabbit Polyclonal antibody specifically detects Influenza A NS1 in . It exhibits reactivity toward Avian Influenza Virus.

Quick Overview for Influenza A NS1 antibody (ABIN7794992)

Target: Influenza A NS1 (NS1) (Influenza Non Structural 1 (NS1))

Reactivity: Avian Influenza Virus

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Influenza A NS1 antibody is un-conjugated

Application: Please inquire

Product Details anti-Influenza A NS1 Antibody

Purpose: Anti-Avian Influenza Nonstructural Protein 1(H5N1 NS1)

Specificity: Rabbit Anti-H5N1 NS1 recognizes H5N1 NS1. This polyclonal antibody was purified using affinity chromatography. Background Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA. Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals, however, it is in birds that all subtypes, including the so-called ?avian flu? or H5N1, can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. One of the less studied proteins encoded by, but not incorporated in, the influenza virus is the nonstructural protein (NS) 1. NS1 counters cellular antiviral activities and acts as a virulence factor. It can bind to double-stranded RNA and sequester it from 2?-5? OAS, preventing the activation of the RNAse L, which normally acts to degrade RNA and prevent virus replication. NS1 also binds to and inhibits the anti-viral protein kinase PKR.

Application Details

Restrictions: For Research Use only

Handling

Concentration: 0.5 μg/mL

Buffer: This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02 % sodium azide as a preservative.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.

Target Details for Influenza A NS1

Target: Influenza A NS1 (NS1) (Influenza Non Structural 1 (NS1))

Alternative Name: Avian Influenza Nonstructural Protein 1

Target Type: Influenza Protein