Rabbit Anti- Severe Acute Respiratory Syndrome Spike (SARS-CoV Spike) recognizes an epitope in the intermediate domain of SARS Spike. This polyclonal antibody was purified using affinity chromatography. Background A novel coronavirus has recently been identified as the causative agent of SARS-CoV.1-2 Coronaviruses are a major cause of upper respiratory diseases in humans.3 The genomes of these viruses are positive-stranded RNA approximately 27-31kb in length. SARS infection can be mediated by the binding of the viral spike protein, a glycosylated 139 kDa protein and the major surface antigen of the virus, to the angiotensin-converting enzyme 2 (ACE2) on target cells. This binding can be blocked by a soluble form of ACE2.4
SARS-CoV S
Reactivity: SARS Coronavirus (SARS-CoV), Virus
ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
Restrictions
For Research Use only
Concentration
0.5 μg/mL
Buffer
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02 % sodium azide as a preservative.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Target
SARS-CoV Spike (SARS-CoV S)
(SARS-Coronavirus Spike Protein (SARS-CoV S))