Recombinant CD3E (Muromonab Biosimilar) antibody

Catalog No. ABIN7795115

This Mouse Monoclonal antibody specifically detects CD3E (Muromonab Biosimilar) in FACS and in vivo. It exhibits reactivity toward Human.

Quick Overview for Recombinant CD3E (Muromonab Biosimilar) antibody (ABIN7795115)

Target: CD3E (Muromonab Biosimilar)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD3E (Muromonab Biosimilar) antibody is un-conjugated

Application: Flow Cytometry (FACS), In vivo Studies (in vivo)

Grade: Research Grade

Product Details anti-CD3E (Muromonab Biosimilar) Antibody

Expression System: Mammalian cells

Purpose: Muromonab Biosimilar, CD3 Monoclonal Antibody

Characteristics: Muromonab Biosimilar uses the same protein sequences as the therapeutic antibody muromonab (OKT3). Muromonab (OKT-3) is a monoclonal anti-CD3 antibody used as immunosuppressive therapy in kidney, heart, and liver transplant patients. Murine monoclonal antibody specific to CD3 T-cell lymphocyte antigens. More specifically it is a purified murine (mouse) monoclonal antibody, directed against the CD3 (T3) receptor on the surface of human T-cells (T-lymphocytes) cultured using the murine ascites method. Muromonab is 93 % monomeric immune globulin G type 2a (IgG2a). Muromonab binds to the T-cell surface glycoprotein CD3 epsilon chain. It appears to kill CD-3 positive cells by inducing Fc mediated apoptosis, antibody mediated cytotoxicity and complement-dependent cytotoxicity.

Purification: Protein A or G affinity column

Purity: >95 % by reducing SDS-PAGE

Endotoxin Level: < 1 EU per 1 mg of the protein by the LAL method

Immunogen: Human CD3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: > 3 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.

Target Details for CD3E (Muromonab Biosimilar)

Target: CD3E (Muromonab Biosimilar)

Alternative Name: Muromonab Biosimilar

Target Type: Biosimilar