Recombinant IL-4RA (Dupilumab Biosimilar) antibody

Catalog No. ABIN7795142

This Mouse Monoclonal antibody specifically detects IL-4RA (Dupilumab Biosimilar) in FACS and in vivo. It exhibits reactivity toward Human.

Quick Overview for Recombinant IL-4RA (Dupilumab Biosimilar) antibody (ABIN7795142)

Target: IL-4RA (Dupilumab Biosimilar)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL-4RA (Dupilumab Biosimilar) antibody is un-conjugated

Application: Flow Cytometry (FACS), In vivo Studies (in vivo)

Grade: Research Grade

Product Details anti-IL-4RA (Dupilumab Biosimilar) Antibody

Expression System: Mammalian cells

Purpose: Dupilumab Biosimilar, Endotoxin 0.05 EU/mg

Characteristics: What is dupilumab biosimilar research grade? Dupilumab is a monoclonal antibody blocking interleukin 4 and interleukin 13, used for allergic diseases such as eczema (atopic dermatitis), asthma and nasal polyps which result in chronic sinusitis. It is also used for the treatment of eosinophilic esophagitis and prurigo nodularis. Dupilumab binds to the alpha subunit of the interleukin-4 receptor (IL-4Ra), making it a receptor antagonist. Through blockade of IL-4Ra, dupilumab modulates signaling of both the interleukin 4 and interleukin 13 pathways. Dupilumab biosimilar uses the same protein sequences as the therapeutic antibody dupilumab.

Purification: Protein A or G affinity column

Purity: >95 % by reducing SDS-PAGE

Endotoxin Level: Less than 0.5 EU/mg of protein as determined by LAL method

Immunogen: Human IL4R alpha

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: > 3 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.

Target Details for IL-4RA (Dupilumab Biosimilar)

Target: IL-4RA (Dupilumab Biosimilar)

Alternative Name: Dupilumab Biosimilar

Target Type: Biosimilar