Recombinant CEACAM5 (Tusamitamab Biosimilar) antibody

Catalog No. ABIN7795147

This anti-CEACAM5 (Tusamitamab Biosimilar) antibody is a Humanized Monoclonal antibody detecting CEACAM5 (Tusamitamab Biosimilar) in FACS and in vivo. Suitable for Human.

Quick Overview for Recombinant CEACAM5 (Tusamitamab Biosimilar) antibody (ABIN7795147)

Target: CEACAM5 (Tusamitamab Biosimilar)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Humanized

Clonality: Monoclonal

Conjugate: This CEACAM5 (Tusamitamab Biosimilar) antibody is un-conjugated

Application: Flow Cytometry (FACS), In vivo Studies (in vivo)

Grade: Research Grade

Product Details anti-CEACAM5 (Tusamitamab Biosimilar) Antibody

Expression System: Mammalian cells

Purpose: Tusamitamab Biosimilar, Human CEACAM5 Monoclonal Antibody

Characteristics: What is tusamitamab biosimilar research grade? Tusamitamab is a humanized IgG1-kappa monoclonal antibody targeting carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) which is overexpressed in tumors including non-small cell lung cancer (NSCLC) and pancreatic ductal adenocarcinoma (PDAC), and is an attractive target for therapies based on CAR-T cell or/and ADCs. Tusamitamab ravtansine (SAR408701) is an antibody-drug conjugate (ADC) combining a humanized monoclonal antibody and a potent cytotoxic maytansinoid derivative (DM4) inhibiting microtubule assembly. Tusamitamab biosimilar uses the same protein sequences as the therapeutic antibody tusamitamab.

Purification: Protein A or G affinity column

Purity: >95 % by reducing SDS-PAGE

Endotoxin Level: < 1 EU per 1 mg of the protein by the LAL method

Immunogen: Human CEACAM5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: > 3 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.

Target Details for CEACAM5 (Tusamitamab Biosimilar)

Target: CEACAM5 (Tusamitamab Biosimilar)

Alternative Name: Tusamitamab Biosimilar

Target Type: Biosimilar