Recombinant CD3 epsilon antibody

Catalog No. ABIN7795360

This anti-CD3 epsilon antibody is a Mouse Monoclonal antibody detecting CD3 epsilon in ELISA, Func, Neut and IGA. Suitable for Human.

Quick Overview for Recombinant CD3 epsilon antibody (ABIN7795360)

Target: CD3 epsilon (CD3E)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD3 epsilon antibody is un-conjugated

Application: ELISA, Functional Studies (Func), Neutralization (Neut), Immunogenicity Assay (IGA)

Grade: In vivo Grade

Clone: 12F6

Product Details anti-CD3 epsilon Antibody

Expression System: Mammalian cells

Purpose: In vivo Grade Recombinant Anti-human CD3e Monoclonal Antibody (Clone: 12F6), Mouse IgG2a Kappa

Characteristics: The 12F6 antibody competes with the OKT3 antibody for binding to human T cells, and has more effective T-cell suppression and activation properties than OKT3. The 12F6 antibody is used to study T-cell functions and to manipulate T-cell activation and suppression, prevent acute allograft rejection, and treat autoimmune diabetes.

Purification: Protein A or G affinity column

Purity: >95 % by reducing SDS-PAGE

Endotoxin Level: < 1 EU per 1 mg of the protein by the LAL method

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: > 3 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.

Target Details for CD3 epsilon

Target: CD3 epsilon (CD3E)

Alternative Name: CD3e

Pathways: TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway