Ectodysplasin A antibody (AA 131-230)

Catalog No. ABIN738381

This anti-Ectodysplasin A antibody is a Rabbit Polyclonal antibody detecting Ectodysplasin A in WB, ELISA, FACS, IF (cc), IF (p), IHC (p), ICC and IHC (fro). Suitable for Human, Mouse and Rat. This Primary Antibody has been cited in 1 publication.

Quick Overview for Ectodysplasin A antibody (AA 131-230) (ABIN738381)

Target: Ectodysplasin A (EDA)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ectodysplasin A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Ectodysplasin A Antibody

Binding Specificity: AA 131-230

Specificity: This will recognize both the membrane bound and the secreted form of Ectodysplasin.

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human of human ED-1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Ectodysplasin A antibody (ABIN738381)

Oya, Yokoyama, Kokuryo, Uno, Yamauchi, Nagino: "Inhibition of Toll-like receptor 4 suppresses liver injury induced by biliary obstruction and subsequent intraportal lipopolysaccharide injection." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 306, Issue 3, pp. G244-52, (2014) (PubMed).

Target Details for Ectodysplasin A

Target: Ectodysplasin A (EDA)

Alternative Name: EDA

Background:

Synonyms: ED1, HED, EDA1, EDA2, HED1, ODT1, XHED, ECTD1, XLHED, ED1-A1, ED1-A2, EDA-A1, EDA-A2, STHAGX1, Ectodysplasin-A, Ectodermal dysplasia protein, EDA protein, EDA

Background: Seems to be involved in epithelial-mesenchymal signaling during morphogenesis of ectodermal organs. Isoform 1 binds only to the receptor EDAR, while isoform 3 binds exclusively to the receptor XEDAR.

Gene ID: 1896

UniProt: Q92838

Pathways: Tube Formation