Anti-Granzyme M/GZMM Antibody catalog # A08286-2. Tested in IHC applications. This antibody reacts with Human.
Purification
Immunogen affinity purified.
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human Granzyme M/GZMM. Human Granzyme M/GZMM shares 85.7% amino acid (aa) sequence identity with rat Granzyme M/GZMM.
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
Target
GZMM
(Granzyme M (Lymphocyte Met-Ase 1) (GZMM))
Alternative Name
GZMM
Background
Human natural killer (NK) cells and activated lymphocytes express and store a distinct subset of neutral serine proteases together with proteoglycans and other immune effector molecules in large cytoplasmic granules. These serine proteases are collectively termed granzymes and include 4 distinct gene products: granzyme A, granzyme B, granzyme H, and the protein encoded by this gene, granzyme M. Two transcript variants encoding different isoforms have been found for this gene.