KLHL12 antibody (AA 23-327)

Catalog No. ABIN7825493

This anti-KLHL12 antibody is a Rabbit Polyclonal antibody detecting KLHL12 in WB. Suitable for Zebrafish (Danio rerio).

Quick Overview for KLHL12 antibody (AA 23-327) (ABIN7825493)

Target: KLHL12 (Kelch-Like 12 (Drosophila) (KLHL12))

Reactivity: Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLHL12 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KLHL12 Antibody

Binding Specificity: AA 23-327

Purpose: Anti-Zebrafish KLHL12 Antibody

Characteristics: Anti-Zebrafish KLHL12 Antibody catalog #AZQ5U374. Tested in WB applications. This antibody reacts with Zebrafish. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived zebrafish KLHL12 recombinant protein (Position: R23-V327)

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Zebrafish

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for KLHL12

Target: KLHL12 (Kelch-Like 12 (Drosophila) (KLHL12))

Alternative Name: KLHL12

Background: Kelch-like protein 12 is a protein that in humans is encoded by the KLHL12 gene. This gene encodes a member of the KLHL (Kelch-like) family of proteins. This protein has been identified as an autoantigen in the autoimmune disease Sjogren's syndrome and as a potential biomarker in primary biliary cirrhosis. This protein may act as a substrate adaptor of the Cullin-3 ubiquitin ligase complex to promote substrate-specific ubiquitylation. Ubiquitylation by this complex has been shown to regulate the Wnt signaling pathway as well as COPII vesicle coat size. A pseudogene has been identified on chromosome 22. Alternative splicing results in multiple transcript variants.

UniProt: Q5U374