TMED10 antibody (AA 27-194)
Quick Overview for TMED10 antibody (AA 27-194) (ABIN7825970)
Target
See all TMED10 AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- AA 27-194
-
Purpose
- Anti-TMP21/TMED10 Antibody
-
Cross-Reactivity (Details)
- No cross-reactivity with other proteins
-
Characteristics
- Anti-TMP21/TMED10 Antibody catalog # A07234-3. Tested in WB, IHC, IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
-
Purification
- Immunogen affinity purified.
-
Immunogen
- E.coli-derived human TMP21/TMED10 recombinant protein (Position: R27-M194). Human TMP21/TMED10 shares 97% amino acid (aa) sequence identity with both mouse and rat TMP21/TMED10.
-
Isotype
- IgG
-
-
-
-
Application Notes
-
Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
Concentration
- 500 μg/mL
-
Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
Storage
- 4 °C,-20 °C
-
Storage Comment
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- TMED10 (Transmembrane Emp24-Like Trafficking Protein 10 (TMED10))
-
Alternative Name
- TMED10
-
Background
- This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.
-
Molecular Weight
- 149 kDa
-
Gene ID
- 10972
-
UniProt
- P49755
Target
-