ICOSLG antibody (AA 19-120)

Catalog No. ABIN740745

This anti-ICOSLG antibody is a Rabbit Polyclonal antibody detecting ICOSLG in WB, ELISA and FACS. Suitable for Human and Mouse. This Primary Antibody has been cited in 1 publication.

Quick Overview for ICOSLG antibody (AA 19-120) (ABIN740745)

Target: ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ICOSLG antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-ICOSLG Antibody

Binding Specificity: AA 19-120

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from Rat ICOS-L

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-ICOSLG antibody (ABIN740745)

Ma, Sun, Zhai, Yu, Wang, Li, Ding: "Effect of follicular helper T cells on the pathogenesis of asthma." in: Experimental and therapeutic medicine, Vol. 14, Issue 2, pp. 967-972, (2017) (PubMed).

Target Details for ICOSLG

Target: ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))

Alternative Name: ICOS-L/B7-H2/CD275

Background:

Synonyms: B7H2, GL50, B7-H2, B7RP1, CD275, ICOSL, LICOS, B7RP-1, ICOS-L, ICOS ligand, B7 homolog 2, B7-like protein Gl50, B7-related protein 1, ICOSLG, KIAA0653

Background: Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion, induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (By similarity).

Gene ID: 23308

UniProt: O75144

Pathways: Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation