TRIM63 antibody (AA 251-353) (FITC)

Catalog No. ABIN741757

This Rabbit Polyclonal antibody specifically detects TRIM63 in WB, FACS, IF (cc) and IF (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for TRIM63 antibody (AA 251-353) (FITC) (ABIN741757)

Target: TRIM63 (Tripartite Motif Containing 63 (TRIM63))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM63 antibody is conjugated to FITC

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-TRIM63 Antibody (FITC)

Binding Specificity: AA 251-353

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MuRF1/Trim63

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for TRIM63

Target: TRIM63 (Tripartite Motif Containing 63 (TRIM63))

Alternative Name: Murf1/Trim63

Background:

Synonyms: MuRF 1, MuRF-1, Muscle-specic RING finger protein 1, Muscle-specic RING finger protein 1, E3 ubiquitin-protein ligase TRIM63, FLJ32380, IRF, MURF1, MURF 1, MURF2, RNF28, SMRZ, Iris ring finger protein, Muscle specic ring finger protein 2, Ring finger protein 28, RNF28, SMRZ, Striated muscle RING zinc finger protein, TRIM 63, TRIM63, Tripartite mot containing 63, Tripartite mot containing protein 63, Ubiquitin ligase TRIM63.

Background: This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is localized to the Z-line and M-line lattices of myofibrils, where titin's N-terminal and C-terminal regions respectively bind to the sarcomere. In vitro binding studies have shown that this protein also binds directly to titin near the region of titin containing kinase activity. Another member of this protein family binds to microtubules. Since these family members can form heterodimers, this suggests that these proteins may serve as a link between titin kinase and microtubule-dependent signal pathways in muscle. [provided by RefSeq].

Gene ID: 84676