Histone 3 antibody (pSer11)
Quick Overview for Histone 3 antibody (pSer11) (ABIN742553)
Target
See all Histone 3 (H3) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- pSer11
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Cross-Reactivity
- Human, Mouse, Rat
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Predicted Reactivity
- Cow,Pig,Rabbit,Drosophila
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Purification
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic phosphopeptide derived from human Histone H3 around the phosphorylation site of Ser11
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Isotype
- IgG
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Application Notes
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ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Expiry Date
- 12 months
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- Histone 3 (H3) (Histone H3 (H3))
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Alternative Name
- Histone H3
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Background
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Synonyms: H3t, H3.4, H3/g, H3FT, Histone H3.1t, H3/t, HIST3H3
Background: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
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Gene ID
- 8290
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UniProt
- Q16695
Target
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