KRT17 antibody (pSer44) (Cy5.5)

Catalog No. ABIN743353

This Rabbit Polyclonal antibody specifically detects KRT17 in WB, IF (cc) and IF (p). It exhibits reactivity toward Human.

Quick Overview for KRT17 antibody (pSer44) (Cy5.5) (ABIN743353)

Target: KRT17 (Keratin 17 (KRT17))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KRT17 antibody is conjugated to Cy5.5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-KRT17 Antibody (Cy5.5)

Binding Specificity: pSer44

Predicted Reactivity: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human CK 17 around the phosphorylation site of Ser44

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for KRT17

Target: KRT17 (Keratin 17 (KRT17))

Alternative Name: CK17

Background:

Synonyms: CK17 phospho S44, CK17 phospho Ser44, p-CK17 Ser44, 39.1, CK 17, Cytokeratin17, K17, Keratin 17 antibody Keratin type I cytoskeletal 17, keratin, type I cytoskeletal 17, Keratin17, KRT 17, KRT17, KRT17 protein, PC, PC2, PCHC1, K1C17_HUMAN.

Background: The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21.This gene encodes the type I intermediate filament chain keratin 17, expressed in nail bed, hair follicle, sebaceous glands, and other epidermal appendages. Mutations in this gene lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex. [provided by RefSeq, Aug 2008].

Gene ID: 3872