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MAP2K7 antibody (pSer271, pThr275) (Biotin)

MAP2K7 Reactivity: Human, Mouse, Rat WB, IHC (p), IHC (fro) Host: Rabbit Polyclonal Biotin
Catalog No. ABIN743920
$451.08
Plus shipping costs $50.00
100 μL
Shipping to: United States
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  • Target See all MAP2K7 Antibodies
    MAP2K7 (Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))
    Binding Specificity
    • 19
    • 18
    • 9
    • 8
    • 8
    • 7
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer271, pThr275
    Reactivity
    • 80
    • 54
    • 44
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 78
    • 5
    Rabbit
    Clonality
    • 70
    • 13
    Polyclonal
    Conjugate
    • 46
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This MAP2K7 antibody is conjugated to Biotin
    Application
    • 58
    • 38
    • 24
    • 17
    • 15
    • 14
    • 12
    • 10
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Predicted Reactivity
    Dog,Cow,Pig
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human MKK7 around the phosphorylation site of Ser271/Thr275
    Isotype
    IgG
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C
    Expiry Date
    12 months
  • Target
    MAP2K7 (Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))
    Alternative Name
    MKK7 + (MAP2K7 Products)
    Synonyms
    MAP2K7 antibody, 2 antibody, JNKK antibody, Jnkk2 antibody, Mapkk7 antibody, Mek7 antibody, Mkk7 antibody, MAPKK7 antibody, MKK7 antibody, PRKMK7 antibody, SAPKK-4 antibody, SAPKK4 antibody, 5930412N11Rik antibody, JNKK 2 antibody, MAPKK 7 antibody, MEK 7 antibody, Prkmk7 antibody, sek2 antibody, si:ch211-254d18.2 antibody, map2k7-A antibody, mitogen-activated protein kinase kinase 7 antibody, mitogen activated protein kinase kinase 7 antibody, mitogen-activated protein kinase kinase 7 L homeolog antibody, MAP2K7 antibody, Map2k7 antibody, map2k7 antibody, map2k7.L antibody
    Background

    The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found, but only one transcript variant has been supported and defined. [provided by RefSeq, Jul 2008].

    Subcellular location: Cytoplasm, Nucleus

    Synonyms: MEK7 phospho S277 + T275, MEK7 phospho Ser277 + Thr275, p-MEK7 S277 + T275, p-MEK7 Ser277 + Thr275, c-Jun N-terminal kinase kinase 2, Dual specicity mitogen activated protein kinase kinase 7, Dual specicity mitogen-activated protein kinase kinase 7, JNK activating kinase 2, JNK kinase 2, JNK-activating kinase 2, Jnkk 2, Jnkk-2, Jnkk2, MAP kinase kinase 7, MAP2K7, MAPK/ERK kinase 7, MAPKK 7, MAPKK-7, MAPKK7, MEK 7, Mitogen Activated Protein Kinase kinase 7, MKK 7, MKK-7, MKK7, MP2K7_HUMAN, PRKMK 7, PRKMK-7, PRKMK7, Sek 2, Sek-2, Sek2.

    Gene ID
    5609
    Pathways
    MAPK Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, BCR Signaling
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