PLCB3 antibody (pSer1105) (HRP)

Catalog No. ABIN744887

The Rabbit Polyclonal anti-PLCB3 antibody has been validated for WB, ELISA, IHC (p) and IHC (fro). It is suitable to detect PLCB3 in samples from Human.

Quick Overview for PLCB3 antibody (pSer1105) (HRP) (ABIN744887)

Target: PLCB3 (phospholipase C, beta 3 (Phosphatidylinositol-Specific) (PLCB3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLCB3 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-PLCB3 Antibody (HRP)

Binding Specificity: pSer1105

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human PLC beta3 around the phosphorylation site of Ser1105

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PLCB3

Target: PLCB3 (phospholipase C, beta 3 (Phosphatidylinositol-Specific) (PLCB3))

Alternative Name: PLC beta3

Background:

Synonyms: Phospholipase C beta 3, Phospholipase C beta 3 phosphatidylinositol specic, PLC beta 3, PLCB3 antibody 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase beta 3, Phosphoinositide phospholipase C, PLCB3_HUMAN.

Background: Phospholipase C is a key enzyme in phosphatidylinositol (PIP2) metabolism and lipid signaling pathways. The Phospholipase C family consists of 13 isozymes split between six subfamilies. Phospholipase C beta is activated by G protein subunits.

Gene ID: 5331

Pathways: WNT Signaling, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, CXCR4-mediated Signaling Events, G-protein mediated Events