PEA15 antibody (AA 51-130) (Cy7)

Catalog No. ABIN747629

The Rabbit Polyclonal anti-PEA15 antibody has been validated for IF (cc) and IF (p). It is suitable to detect PEA15 in samples from Human.

Quick Overview for PEA15 antibody (AA 51-130) (Cy7) (ABIN747629)

Target: PEA15 (phosphoprotein Enriched in Astrocytes 15 (PEA15))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PEA15 antibody is conjugated to Cy7

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-PEA15 Antibody (Cy7)

Binding Specificity: AA 51-130

Predicted Reactivity: Human,Mouse,Rat,Dog,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PEA15

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PEA15

Target: PEA15 (phosphoprotein Enriched in Astrocytes 15 (PEA15))

Alternative Name: PEA15

Background:

Synonyms: Astrocytic phosphoprotein PEA 15, Astrocytic phosphoprotein PEA15, HMAT 1, HMAT1, Homolog of mouse MAT 1 oncogene, Homolog of mouse MAT1 oncogene, HUMMAT 1H, HUMMAT1H, MAT 1, MAT 1H, MAT1, MAT1H, PEA 15, PEA-15_ PEA15 protein, PED, Phosphoprotein enriched in astrocytes 15, Phosphoprotein enriched in astrocytes 15kD, Phosphoprotein enriched in diabetes, PEA15_HUMAN.

Background: PED/PEA 15 (Phosphoprotein Enriched in Diabetes/Phosphoprotein Enriched in Astrocytes 15 kDa) is a widely expressed 15 kDa protein comprised of an N terminal region containing a canonical Death Effector Domain (DED) sequence and a nuclear export signal, and a C terminal region containing two serine phosphorylation sites. PED/PEA 15 has been implicated in the regulation of multiple cellular processes including apoptosis, integrin activation, and insulin sensitive glucose transport in insulin responsive cells. Phosphorylation of both serine 104 (a Protein Kinase C site) and serine 116 (a substrate of CaMKII and Akt) is required for PED/PEA 15 function.

Gene ID: 8682