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IL12RB2 antibody (Interleukin 12 Receptor, beta 2) (AA 301-400) Primary Antibody

IL12RB2 Reactivity: Human ELISA, IF (cc), IF (p), IHC (fro), WB Host: Rabbit Polyclonal unconjugated
Pubmed (1)
Catalog No. ABIN747878
$339.90
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 4 to 6 Business Days
  • Target
    IL12RB2
    Binding Specificity
    • 16
    • 14
    • 9
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 301-400
    Reactivity
    • 60
    • 11
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 56
    • 11
    Rabbit
    Clonality
    • 58
    • 9
    Polyclonal
    Conjugate
    • 28
    • 8
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL12RB2 antibody is un-conjugated
    Application
    • 44
    • 28
    • 21
    • 20
    • 12
    • 12
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
    Cross-Reactivity
    Chicken, Cow, Horse, Mouse, Pig, Rabbit, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human IL-12RB2
    Isotype
    IgG
  • Application Notes
    WB 1:300-1000
    ELISA 1:500-1000
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C
    Expiry Date
    12 months
  • Filková, Vernerová, Hulejová, Prajzlerová, Veigl, Pavelka, Vencovský, Šenolt: "Pro-inflammatory effects of interleukin-35 in rheumatoid arthritis." in: Cytokine, Vol. 73, Issue 1, pp. 36-43, 2015 (PubMed). Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Human).

  • Target
    IL12RB2
    Alternative Name
    IL12RB2 (IL12RB2 Antibody Abstract)
    Synonyms
    IL12RB2, A930027I18Rik, IL-12RB2, Ifnm, interleukin 12 receptor subunit beta 2, interleukin 12 receptor, beta 2, IL12RB2, Il12rb2
    Background

    Receptor for interleukin-12. This subunit is the signaling component coupling to the JAK2/STAT4 pathway. Promotes the proliferation of T-cells as well as NK cells. Induces the promotion of T-cells towards the Th1 phenotype by strongly enhancing IFN-gamma production.

    Subcellular location: Cell membrane

    Synonyms: Interleukin-12 receptor subunit beta-2, IL-12 receptor subunit beta-2, IL-12R subunit beta-2, IL-12R-beta-2, IL-12RB2, IL12RB2

    Gene ID
    3595
    UniProt
    Q99665
    Pathways
    JAK-STAT Signaling
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