DKK3 antibody (AA 31-130) (Biotin)
Quick Overview for DKK3 antibody (AA 31-130) (Biotin) (ABIN749125)
Target
See all DKK3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 31-130
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Cross-Reactivity
- Mouse, Rabbit
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Predicted Reactivity
- Human,Rat,Cow,Pig,Horse
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Purification
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human DKK3
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Isotype
- IgG
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Application Notes
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C for 12 months.
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Expiry Date
- 12 months
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- DKK3
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Background
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Synonyms: RIG, REIC, Dickkopf-related protein 3, Dickkopf-3, Dkk-3, hDkk-3, DKK3, UNQ258/PRO295
Background: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).
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Gene ID
- 27122
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UniProt
- Q9UBP4
Target
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