NCF2 antibody (AA 101-200) (HRP)

Catalog No. ABIN750727

This Rabbit Polyclonal antibody specifically detects NCF2 in ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for NCF2 antibody (AA 101-200) (HRP) (ABIN750727)

Target: NCF2 (Neutrophil Cytosolic Factor 2 (NCF2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCF2 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-NCF2 Antibody (HRP)

Binding Specificity: AA 101-200

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NOXA2

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for NCF2

Target: NCF2 (Neutrophil Cytosolic Factor 2 (NCF2))

Alternative Name: NOXA2/p67phox

Background:

Synonyms: NCF-2, Ncf2, Neutrophil NADPH oxidase factor 2, NOXA2, p67-phox, p67phox, neutrophil cytosol factor 2 isoform 1, neutrophil cytosolic factor 2 65kD, chronic granulomatous disease, autosomal 2, NADPH oxidase activator 2, neutrophil cytosol factor 2, 67 kDa neutrophil oxidase factor.

Background: This gene encodes neutrophil cytosolic factor 2, the67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq].

Gene ID: 4688