MAVS antibody (AA 3-100)

Catalog No. ABIN753133

This Rabbit Polyclonal antibody specifically detects MAVS in WB, ELISA, IHC (p), IF (cc), IF (p) and IHC (fro). It exhibits reactivity toward Mouse.

Quick Overview for MAVS antibody (AA 3-100) (ABIN753133)

Target: MAVS (Mitochondrial Antiviral Signaling Protein (MAVS))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAVS antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-MAVS Antibody

Binding Specificity: AA 3-100

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Cow

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MAVS

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for MAVS

Target: MAVS (Mitochondrial Antiviral Signaling Protein (MAVS))

Alternative Name: MAVS

Background:

Synonyms: CARD adapter inducing interferon beta, Card, Interferon beta promoter stimulator protein 1, Interferon-beta promoter stimulator protein 1, Ips 1, Ips1, KIAA1271, Mitochondrial anti viral signaling protein, Mitochondrial Antiviral Signaling, Mitochondrial antiviral signaling protein, Putative NF kappa B activating protein 031N, Virus induced signaling adapter, DKFZp547C224, DKFZp666M015, FLJ27482, FLJ31698, FLJ35386, FLJ38051, CARD, FLJ41962, IPS-1, IPS1, MGC3260, VISA, MAVS_HUMAN.

Background: MAVS (Mitochondrial Antiviral Signaling) mediates the activation of NF-kappaB and IRF3 in response to antiviral infection. Silencing of MAVS expression permits derepression of viral replication, while over expression of MAVS boosts antiviral immunity.

Gene ID: 5788

Pathways: Activation of Innate immune Response, Inositol Metabolic Process, Hepatitis C