MAVS antibody (AA 3-100) (HRP)

Catalog No. ABIN753142

This Rabbit Polyclonal antibody specifically detects MAVS in WB, ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Mouse.

Quick Overview for MAVS antibody (AA 3-100) (HRP) (ABIN753142)

Target: MAVS (Mitochondrial Antiviral Signaling Protein (MAVS))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAVS antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-MAVS Antibody (HRP)

Binding Specificity: AA 3-100

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Cow

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MAVS

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MAVS

Target: MAVS (Mitochondrial Antiviral Signaling Protein (MAVS))

Alternative Name: MAVS

Background:

Synonyms: CARD adapter inducing interferon beta, Card, Interferon beta promoter stimulator protein 1, Interferon-beta promoter stimulator protein 1, Ips 1, Ips1, KIAA1271, Mitochondrial anti viral signaling protein, Mitochondrial Antiviral Signaling, Mitochondrial antiviral signaling protein, Putative NF kappa B activating protein 031N, Virus induced signaling adapter, DKFZp547C224, DKFZp666M015, FLJ27482, FLJ31698, FLJ35386, FLJ38051, CARD, FLJ41962, IPS-1, IPS1, MGC3260, VISA, MAVS_HUMAN.

Background: MAVS (Mitochondrial Antiviral Signaling) mediates the activation of NF-kappaB and IRF3 in response to antiviral infection. Silencing of MAVS expression permits derepression of viral replication, while over expression of MAVS boosts antiviral immunity.

Gene ID: 5788

Pathways: Activation of Innate immune Response, Inositol Metabolic Process, Hepatitis C