TWF1 antibody (AA 351-422) (Biotin)

Catalog No. ABIN754845

This anti-TWF1 antibody is a Rabbit Polyclonal antibody detecting TWF1 in WB, ELISA, IHC (p) and IHC (fro). Suitable for Human.

Quick Overview for TWF1 antibody (AA 351-422) (Biotin) (ABIN754845)

Target: TWF1 (Twinfilin, Actin-Binding Protein 1 (TWF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TWF1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-TWF1 Antibody (Biotin)

Binding Specificity: AA 351-422

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Cow,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TWF1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for TWF1

Target: TWF1 (Twinfilin, Actin-Binding Protein 1 (TWF1))

Alternative Name: PTK9

Background:

Synonyms: A6, A6 protein tyrosine kinase, Protein A6, Protein tyrosine kinase 9, PTK9, PTK9 protein tyrosine kinase 9, TWF 1, TWF1, Twinfilin 1, Twinfilin actin binding protein, homolog 1, Twinfilin, Twinfilin, actin-binding protein, homolog 1 Drosophila, Twinfilin, Drosophila, homolog of, 1, TWF1_HUMAN, Twinfilin-1.

Background: PTK9 is an actin-binding protein involved in motile and morphological processes. It inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. PTK9 seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles.

Gene ID: 5756

UniProt: Q12792

Pathways: Regulation of Actin Filament Polymerization, Maintenance of Protein Location