Angiomotin antibody (AA 545-620)

Catalog No. ABIN754873

This Rabbit Polyclonal antibody specifically detects Angiomotin in WB, ELISA, IHC (p), IF (cc), IF (p) and IHC (fro). It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for Angiomotin antibody (AA 545-620) (ABIN754873)

Target: Angiomotin (AMOT)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Angiomotin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Angiomotin Antibody

Binding Specificity: AA 545-620

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Angiomotin

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Angiomotin antibody (ABIN754873)

Shimada, Abe, Kohno, Satohisa, Konno, Takahashi, Hatakeyama, Arimoto, Kakuki, Kaneko, Takano, Saito, Kojima: "Loss of tricellular tight junction protein LSR promotes cell invasion and migration via upregulation of TEAD1/AREG in human endometrial cancer." in: Scientific reports, Vol. 7, pp. 37049, (2017) (PubMed).

Target Details for Angiomotin

Target: Angiomotin (AMOT)

Alternative Name: Angiomotin

Background:

Synonyms: Angiomotin, AMOT, KIAA171

Background: Plays a central role in tight junction maintenance via the complex formed with ARHGAP17, which acts by regulating the uptake of polarity proteins at tight junctions. Appears to regulate endothelial cell migration and tube formation. May also play a role in the assembly of endothelial cell-cell junctions.

Gene ID: 154796

UniProt: Q4VCS5

Pathways: Cell-Cell Junction Organization, Regulation of Cell Size