PTGER2 antibody (AA 271-358)

Catalog No. ABIN755248

This Rabbit Polyclonal antibody specifically detects PTGER2 in WB, ELISA, FACS, IF (cc), IF (p) and IHC (fro). It exhibits reactivity toward Human, Mouse and Sheep and has been mentioned in 3+ publications.

Quick Overview for PTGER2 antibody (AA 271-358) (ABIN755248)

Target: PTGER2 (Prostaglandin E Receptor 2 (Subtype EP2), 53kDa (PTGER2))

Reactivity: Human, Mouse, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTGER2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-PTGER2 Antibody

Binding Specificity: AA 271-358

Cross-Reactivity: Human, Mouse, Sheep

Predicted Reactivity: Rat,Dog,Cow,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Prostaglandin E Receptor EP2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-PTGER2 antibody (ABIN755248)

Takemiya, Takeuchi, Kawakami: "Microsomal Prostaglandin E Synthase-1 Facilitates an Intercellular Interaction between CD4⁺ T Cells through IL-1β Autocrine Function in Experimental Autoimmune Encephalomyelitis." in: International journal of molecular sciences, Vol. 18, Issue 12, (2018) (PubMed).

Müller, Schwab, Rosenfeld, Antonow-Schlorke, Nathanielsz, Rakers, Schubert, Witte, Rupprecht: "Fetal Sheep Mesenteric Resistance Arteries: Functional and Structural Maturation." in: Journal of vascular research, Vol. 54, Issue 5, pp. 259-271, (2017) (PubMed).

Target Details for PTGER2

Target: PTGER2 (Prostaglandin E Receptor 2 (Subtype EP2), 53kDa (PTGER2))

Background:

Synonyms: EP2, Prostaglandin E2 receptor EP2 subtype, PGE receptor EP2 subtype, PGE2 receptor EP2 subtype, Prostanoid EP2 receptor, PTGER2

Background: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle.

Gene ID: 5732

UniProt: P43116