CAPZA1 antibody (AA 201-286) (HRP)

Catalog No. ABIN755746

Product Details anti-CAPZA1 Antibody (HRP)

Target: CAPZA1 (Capping Protein (Actin Filament) Muscle Z-Line, alpha 1 (CAPZA1))

Binding Specificity: AA 201-286

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CAPZA1 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CAPZA1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CAPZA1

Target: CAPZA1 (Capping Protein (Actin Filament) Muscle Z-Line, alpha 1 (CAPZA1))

Alternative Name: CAPZA1 (CAPZA1 Products)

Background:

Synonyms: CAPZ, CAZ1, CAPPA1, F-actin-capping protein subunit alpha-1, CapZ alpha-1, CAPZA1

Background: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.

Gene ID: 829

UniProt: P52907

Pathways: Regulation of Actin Filament Polymerization