FTH1 antibody (AA 1-100)

Catalog No. ABIN759641

The Rabbit Polyclonal anti-FTH1 antibody has been validated for WB, ELISA, FACS, IHC (p) and IHC (fro). It is suitable to detect FTH1 in samples from Human and Mouse. There is 1 publication available.

Quick Overview for FTH1 antibody (AA 1-100) (ABIN759641)

Target: FTH1 (Ferritin, Heavy Polypeptide 1 (FTH1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FTH1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-FTH1 Antibody

Binding Specificity: AA 1-100

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Ferritin heavy chain

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-FTH1 antibody (ABIN759641)

Zhang, Zhao, Chang, Zhang, Chu, Zhang, Liu, Guo, Wang, Gao, Zhang, Chu: "Calcium channel blockers ameliorate iron overload-associated hepatic fibrosis by altering iron transport and stellate cell apoptosis." in: Toxicology and applied pharmacology, Vol. 301, pp. 50-60, (2016) (PubMed).

Target Details for FTH1

Target: FTH1 (Ferritin, Heavy Polypeptide 1 (FTH1))

Alternative Name: Ferritin heavy chain

Background:

Synonyms: FHC, FTH, HFE5, PLIF, FTHL6, PIG15, Ferritin heavy chain, Ferritin H subunit, Cell proliferation-inducing gene 15 protein, FTH1, OK/SW-cl.84

Background: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity).

Gene ID: 2495

UniProt: P02794

Pathways: Transition Metal Ion Homeostasis