CD16a, CD16b (AA 131-230) antibody

Catalog No. ABIN761381

The Rabbit Polyclonal anti- antibody has been validated for WB, FACS, IF (cc), IF (p), ELISA, IHC (fro) and IHC (p). It is suitable to detect in samples from Human, Mouse and Rat. There is 1 publication available.

Quick Overview for CD16a, CD16b (AA 131-230) antibody (ABIN761381)

Target: CD16a, CD16b

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details

Binding Specificity: AA 131-230

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CD16a

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References

Ding, Wang, Wang, Yang, Xue: "Expression of Tumor-Associated Macrophage in Progression of Human Glioma." in: Cell biochemistry and biophysics, (2014) (PubMed).

Target Details

Target: CD16a, CD16b

Alternative Name: CD16a/CD16b

Background:

Synonyms: CD16, FCG3, CD16A, FCGR3, IGFR3, IMD2, FCR-1, FCRIII, FCGRIII, FCRIIIA, Low affinity immunoglobulin gamma Fc region receptor III-A, CD16a antigen, Fc-gamma RIII-alpha, Fc-gamma RIII, Fc-gamma RIIIa, IgG Fc receptor III-2, FCGR3A, FCGR3B, CD16B,

Background: Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis.

Gene ID: 2214

UniProt: P08637