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DIRAS1 antibody (AA 21-120) (Biotin)

This Rabbit Polyclonal antibody specifically detects DIRAS1 in WB, ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Human.
Catalog No. ABIN763348

Quick Overview for DIRAS1 antibody (AA 21-120) (Biotin) (ABIN763348)

Target

See all DIRAS1 Antibodies
DIRAS1 (DIRAS Family, GTP-Binding RAS-Like 1 (DIRAS1))

Reactivity

  • 48
  • 6
  • 6
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Host

  • 47
  • 2
Rabbit

Clonality

  • 49
Polyclonal

Conjugate

  • 22
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DIRAS1 antibody is conjugated to Biotin

Application

  • 38
  • 20
  • 13
  • 13
  • 11
  • 10
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Binding Specificity

    • 14
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    AA 21-120

    Predicted Reactivity

    Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken

    Purification

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human DIRAS1

    Isotype

    IgG
  • Application Notes

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C for 12 months.

    Expiry Date

    12 months
  • Target

    DIRAS1 (DIRAS Family, GTP-Binding RAS-Like 1 (DIRAS1))

    Alternative Name

    DIRAS1

    Background

    Synonyms: Di Ras1, DIRAS family GTP binding RAS like 1, Distinct subgroup of the Ras family member 1, GBTS1, GTP binding protein Di Ras1, Ras related inhibitor of cell growth, RIG, Rig protein, Small GTP binding tumor suppressor 1.

    Background: The three human RAS genes encode highly related 188 to 189 amino acid proteins, designated H-Ras, N-Ras and K-Ras4A and K-Ras4B (the two K-Ras proteins arise from alternative gene splicing). Ras proteins function as binary molecular switches that control intracellular signaling networks. Ras-regulated signal pathways control such processes as actin cytoskeletal integrity, proliferation, differentiation, cell adhesion, apoptosis, and cell migration. Ras and ras-related proteins are often deregulated in cancers, leading to increased invasion and metastasis, and decreased apoptosis.DIRAS1 displays low GTPase activity and exists predominantly in the GTP-bound form. It is highly expressed in heart and brain.

    Gene ID

    148252

    Pathways

    Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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