DIRAS1 antibody (AA 21-120) (Biotin)
Quick Overview for DIRAS1 antibody (AA 21-120) (Biotin) (ABIN763348)
Target
See all DIRAS1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 21-120
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Predicted Reactivity
- Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken
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Purification
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human DIRAS1
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Isotype
- IgG
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Application Notes
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C for 12 months.
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Expiry Date
- 12 months
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- DIRAS1 (DIRAS Family, GTP-Binding RAS-Like 1 (DIRAS1))
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Alternative Name
- DIRAS1
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Background
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Synonyms: Di Ras1, DIRAS family GTP binding RAS like 1, Distinct subgroup of the Ras family member 1, GBTS1, GTP binding protein Di Ras1, Ras related inhibitor of cell growth, RIG, Rig protein, Small GTP binding tumor suppressor 1.
Background: The three human RAS genes encode highly related 188 to 189 amino acid proteins, designated H-Ras, N-Ras and K-Ras4A and K-Ras4B (the two K-Ras proteins arise from alternative gene splicing). Ras proteins function as binary molecular switches that control intracellular signaling networks. Ras-regulated signal pathways control such processes as actin cytoskeletal integrity, proliferation, differentiation, cell adhesion, apoptosis, and cell migration. Ras and ras-related proteins are often deregulated in cancers, leading to increased invasion and metastasis, and decreased apoptosis.DIRAS1 displays low GTPase activity and exists predominantly in the GTP-bound form. It is highly expressed in heart and brain.
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Gene ID
- 148252
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Pathways
- Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
Target
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