Frataxin antibody

Catalog No. ABIN781667

The Mouse Monoclonal anti-Frataxin antibody has been validated for IHC (p). It is suitable to detect Frataxin in samples from Human and Pig.

Quick Overview for Frataxin antibody (ABIN781667)

Target: Frataxin (FXN)

Reactivity: Human, Pig

Host: Mouse

Clonality: Monoclonal

Conjugate: This Frataxin antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 2FRA-1G2

Product Details anti-Frataxin Antibody

Specificity: This Monoclonal antibody Clone 2FRA-1G2 recognizes Human Frataxin. Frataxin is localized to the mitochondrion. Antigen Distribution: The antigen has been described in the heart, peripheral blood lymphocytes and dermal fibroblasts.

Cross-Reactivity (Details): Species reactivity (tested):Human, Pig.

Purification: Affinity Chromatography

Immunogen: TrpE-Frataxin full length.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Restore by adding 0.5 mL distilled water

Concentration: 0.5 mg/mL

Buffer: Stock solution contains PBS, pH 7.2 with 5 mg/mL BSA as stabilizer and 0.01 % Kathon as a preservative

Preservative: Kathon CG

Precaution of Use: This product contains Kathon CG a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Frataxin

Target: Frataxin (FXN)

Background: The function of frataxin is not entirely clear, but it seems to be involved in assembly of iron-sulfur clusters. It has been proposed to act as either an iron chaperone or an iron storage protein.Synonyms: FRDA, Frataxin mitochondrial, Friedreich ataxia protein

Gene ID: 2395

NCBI Accession: NP_000135

UniProt: Q16595

Pathways: Transition Metal Ion Homeostasis, Regulation of Cell Size