Ferritin antibody

Catalog No. ABIN781724

The Mouse Monoclonal anti-Ferritin antibody has been validated for EIA and IHC (fro). It is suitable to detect Ferritin in samples from Human.

Quick Overview for Ferritin antibody (ABIN781724)

Target: Ferritin (FE)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Ferritin antibody is un-conjugated

Application: Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: MAb 44

Product Details anti-Ferritin Antibody

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Affinity chromatography

Immunogen: Ferritin from human spleen and liver

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Reconstitute by adding 0.5 mL distilled water.

Buffer: Stock solution contains 0.4 mg/mL IgG, phosphate buffered saline pH 7.2 (PBS), 10 mg/mL bovine serum albumin (BSA) as a stabilizer and 0.01 % thimerosal as a preservative

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Prior to reconstitution store at 2-8 °C. Following reconstitution store (in aliquots) at -20 °C.

Target Details for Ferritin

Target: Ferritin (FE)

Alternative Name: Ferritin

Background: Ferritin consists of a mineral core of hydrated ferric oxide, and a multi-subunit protein shell which englobes the former and assures its solubility in an aqueous environment. It is mainly localized intracellularly in cells of the reticuloendothelial system as well as in liver, spleen and bone marrow. Elevated serum levels are found in patients with iron overload and in other diseases such as pernicious anaemia, chronic inflammations such as rheumatoid arthritis (RA), hepatocellular carcinoma and Hodgkin's disease. Ferritin consists of two components, the apoferritin and the iron core (FeIII - hydroxyphosphate-micelle). The apoferritin is a globular protein built up of 24 subunits that can bind up to 4500 iron atoms. Other non-ferrous metal ions such as Al or Be can also bind to ferritin, which acts partly as a metal ion detoxicant.Synonyms: FTH, FTL, Ferritin H subunit, Ferritin L subunit

Pathways: Transition Metal Ion Homeostasis