TSG101 antibody

Catalog No. ABIN781822

This Mouse Monoclonal antibody specifically detects TSG101 in WB, IF, IHC (p) and EIA. It exhibits reactivity toward Human.

Quick Overview for TSG101 antibody (ABIN781822)

Target: TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TSG101 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Clone: 5B7

Product Details anti-TSG101 Antibody

Specificity: This antibody reacts to TSG101.

Purification: Protein A chromatography

Immunogen: TSG101 antibody was raised against recombinant protein

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0,5 mg/mL

Buffer: PBS, pH 7.2

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for TSG101

Target: TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Alternative Name: TSG101

Background: The tumor susceptibility gene 101 (TSG101) was first discovered in a screen for potential tumor suppressors. Altered transcripts of this gene have been detected in sporadic breast carcinomas and other malignancies. In mice the gene has been shown to be essential for growth, proliferation and survival of mammary epithelial cells. TSG101 is also a component of the ESCRt-1 complex, a regulator of the vesicular trafficking process. In addition it is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies and is involved the budding of many viruses.Synonyms: ESCRT-I complex subunit TSG101, Tumor susceptibility gene 101 protein

Gene ID: 7251

NCBI Accession: NP_006283

UniProt: Q99816